AMBP antibody (AA 205-349)

Catalog No. ABIN7600577

This anti-AMBP antibody is a Rabbit Polyclonal antibody detecting AMBP in WB and ELISA. Suitable for Rat and Mouse.

Quick Overview for AMBP antibody (AA 205-349) (ABIN7600577)

Target: AMBP (alpha 1 Microglobulin/bikunin precursor (AMBP))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMBP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-AMBP Antibody

Binding Specificity: AA 205-349

Purpose: Anti-Alpha 1 microglobulin/Ambp Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Alpha 1 microglobulin/Ambp Antibody Picoband® (ABIN7600577). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Alpha 1 microglobulin/Ambp recombinant protein (Position: A205-S349).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Diarra-Mehrpour, M., Bourguignon, J., Sesboue, R., Mattei, M.-G., Passage, E., Salier, J.-P., Martin, J.-P. Human plasma inter-alpha-trypsin inhibitor is encoded by four genes on three chromosomes. Europ. J. Biochem. 179: 147-154, 1989. 2. Hochstrasser, K., Bretzel, G., Feuth, H., Hilla, W., Lempart, K. The inter-alpha-trypsin inhibitor as precursor of the acid-stable proteinase inhibitors in human serum and urine. Hoppe Seylers Z. Physiol. Chem. 357: 153-162, 1976. 3. Leveillard, T., Bourguignon, J., Sesboue, R., Hanauer, A., Salier, J. P., Diarra-Mehrpour, M., Martin, J. P. BstXI RFLP in the human inter-alpha-trypsin inhibitor light chain gene. Nucleic Acids Res. 16: 2744 only, 1988.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for AMBP

Target: AMBP (alpha 1 Microglobulin/bikunin precursor (AMBP))

Alternative Name: Ambp

Background:

Synonyms: Protein AMBP, Alpha-1-microglobulin, Protein HC, Alpha-1 microglycoprotein, Complex-forming glycoprotein heterogeneous in charge, Inter-alpha-trypsin inhibitor light chain, ITI-LC, Bikunin, EDC1, HI-30, Uronic-acid-rich protein, Trypstatin, AMBP, HCP, ITIL

Tissue Specificity: Expressed by the liver and secreted in plasma. Alpha-1-microglobulin occurs in many physiological fluids including plasma, urine, and cerebrospinal fluid. Inter-alpha- trypsin inhibitor is present in plasma and urine.

Background: Protein AMBP is a protein that in humans is encoded by the AMBP gene. This gene encodes a fusion protein that undergoes proteolytic processing to generate two mature proteins: alpha-1-microglobulin (A1m) is a heme-binding plasma glycoprotein of the lipocalin superfamily of proteins that bind to hydrophobic molecules, whereas bikunin belongs to the superfamily of Kunitz-type protease inhibitors. The transgenic mice specifically lacking bikunin, but not A1m, exhibit female infertility and an increased sensitivity to lung metastasis.

Molecular Weight: 39 kDa

Gene ID: 11699

UniProt: Q07456